Etiological Tracing Test and Drug Efficacy Test in a Case of Clinical Canine Toxic Liver Disease

Abstract

This experiment is divided into three parts. A typical case report of canine toxic liver disease was recorded at the Huazhong Agricultural University Animal Hospital. The etiology tracing test focused on the daily life risk factors that induced the disease. The pathological model of toxic liver disease in mice was successfully established by the administration of household formaldehyde, floor cleaner and chlorine-containing disinfectant tablets. The drug efficacy test was carried out by the administration of self-made traditional Chinese medicine to the model mice, and to observe the therapeutic effect of traditional Chinese medicine prescription on the mice pathological model.

It can be concluded that the daily life risk factors should be paid enough attention to in the dog's toxic liver disease. In comparison, within households that own dogs, the toxicity of chlorine-containing disinfectant is low in the normal dilution range, and its liver damage to mice is very light during the test. However, caution should be exercised when using floor cleaners and formaldehyde. Self-made traditional Chinese medicine has a good effect on this type of liver disease, but it should also pay attention to the dose, concentration and usage cycle.